in multiple dog breeds using Embark, Wisdom Panel, VGL UC Davis. Laboklin. Embark tests COI. Wisdom Panel and Laboklin test Heterozygosity. VGL tests Internal Relatedness, a grading of inbreeding. All these platforms look at DNA tested amounts of inbreeding of each dog tested.
One of the largest population study ever done, Bannasch et al. (2021), analyzed the genetic coefficient of inbreeding (COI) for 227 of the most common dog breeds. The researchers found that the average COI across these breeds was 0.249 (24.9%). To put this into perspective, a COI of 25% is what you would expect from a brother–sister mating in a population with no prior inbreeding. In other words, the average purebred dog today is genetically as similar as the offspring of two siblings.